Research-Technical Employee in the Department of Biochemistry and Molecular Biology (PACMAN Project – Vacancy 1) (M/F/X)

Description

Offer Description: The Rector of Wroclaw University of Environmental and Life Sciences announces an open competition for the position in the research-technical group (F/M/X) in the project entitled “Personalized antibody-drug conjugates activated by matrix metalloproteinases for solid tumors”, acronym: PACMAN, Virtual Research Institute (WIB); managing entity: Łukasiewicz Research Network – PORT; implemented at the Department of Biochemistry and Molecular Biology Position title: Research-Technical Employee (Technical support) Field: Veterinary Sciences Discipline: Veterinary Science Location: Wroclaw Contract type: Employment contract ( umowa o pracę ) Working time: 1,0 (Full-time) Organisational unit: Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences The PACMAN project develops a new class of antibody–drug conjugates (ADCs) that do not require internalisation and are selectively activated extracellularly by matrix metalloproteinases (MMP‑2, MMP‑9 and MMP‑14) in the microenvironment of solid tumours. Position description: Specialist for assessing the immunogenicity of antibody–drug conjugates (ADCs) using in vitro and in vivo methods. Main tasks and responsibilities: optimisation of methods for assessing the immunogenicity of antibody–drug conjugates (ADCs) using ELISA, ELISPOT and immunopeptidomics techniques in human and animal models; assessment of ADC immunogenicity and reporting of the immunogenicity index for selected ADCs; comparative analysis of ADC immunogenicity parameters for selected MHC haplotypes in the human population; reporting preclinical immunogenicity data for lead ADCs. Requirements: higher education, veterinary medicine degree and experience in conducting preclinical studies using laboratory mice, experience in techniques for the isolation, purification, culture and activation of human leukocytes, experience in high-throughput, automated imaging methods and the assessment of physiological parameters of cell cultures (morphology, viability, proliferation, cytokine release), commitment to comply with the non-compete rules in accordance with the WIB Programme guidelines. Selection criteria: The candidate’s scientific and professional experience, as well as competences to perform tasks within the research project. The scope of previous research activities and their alignment with the subject of the Research Task. The quality and scope of the candidate’s previous scientific achievements, in particular scientific publications, participation in research projects, awards and distinctions received, and references issued by independent scientists. The candidate’s international experience and scientific mobility. The candidate’s soft skills, including teamwork, communication skills, proficiency in English and the alignment of scientific development plans with the goals of the research team. We offer: employment under an employment contract ( umowa o pracę ) for a period of up to 12 months (with the possibility of extending the employment by a further 32 months following a positive performance evaluation; up to a total of 44 months); planned employment start date: 1 November 2026; remuneration consisting of basic salary, a length-of-service allowance (3-20%), an annual additional salary (the so-called “thirteenth salary”), holiday allowance and other variable components provided for in the Remuneration Regulations for Employees of Wrocław University of Environmental and Life Sciences; the opportunity to work on a project with high translational potential; subsidised sports activities; subsidised private medical care; flexible working hours (starting work between 6:00 and 9:00); the possibility of bringing your pet to work; additional days off during the year (the so-called Rector’s Days); Erasmus+ programme for staff; a wide range of training and professional development opportunities. Required documents: CV in the form of a concise

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Source

Source: euraxess.ec.europa.eu