[PAR-27-081] Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)

Description

Titolo: Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed) Numero dell'opportunità: PAR-27-081 Stato: aperto (posted) Tipo di opportunità: Discretionary Ente: National Institutes of Health — Department of Health and Human Services Tipo di finanziamento: Grant Categoria: Health Programma (ALN): 93.242 Mental Health Research Grants; 93.279 Drug Use and Addiction Research Programs; 93.866 Aging Research; 93.867 Vision Research Pubblicato il: 2026-05-04 Scadenza per le domande: 2027-03-05 Cofinanziamento richiesto: no Chi può fare domanda: City or township governments; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Special district governments; Small businesses; Native American tribal governments (Federally recognized); Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; State governments; Public and State controlled institutions of higher education Altre condizioni di eleggibilità: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. Descrizione: The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds.Through this NOFO, NIH wishes to stimulate research in:Discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Eye Institute (NEI), and/or National Institute on Aging (NIA) andDiscovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms.Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes. Contatto: [email protected]

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Source

Source: grants.gov