[PAR-25-442] Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Description

Titolo: Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed) Numero dell'opportunità: PAR-25-442 Stato: aperto (posted) Tipo di opportunità: Discretionary Ente: National Institutes of Health — Department of Health and Human Services Tipo di finanziamento: Grant Categoria: Health Programma (ALN): 93.121 Oral Diseases and Disorders Research; 93.242 Mental Health Research Grants; 93.350 National Center for Advancing Translational Sciences; 93.855 Allergy and Infectious Diseases Research; 93.865 Child Health and Human Development Extramural Research; 93.867 Vision Research Pubblicato il: 2025-06-17 Scadenza per le domande: 2028-02-17 Cofinanziamento richiesto: no Chi può fare domanda: For profit organizations other than small businesses; Special district governments; Public and State controlled institutions of higher education; State governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Native American tribal governments (Federally recognized); Small businesses; County governments; Private institutions of higher education Altre condizioni di eleggibilità: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. Descrizione: The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method or agent that is selective for one or more targets within that target class. This NOFO is intended to jumpstart research that demonstrates innovative strategies to modulate targets that cannot be addressed by established therapeutic types, furthering the development of methods and/or agents selective for undruggable target classes. Annuncio completo: http://grants.nih.gov/grants/guide/pa-files/PAR-25-442.html Contatto: [email protected]

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Source: grants.gov