[CoNbI-OCD] Computational Neuroscience-based Interventions for OCD
Ente: European Commission
Scadenza: 2031-12-31
Importo max: 1.999.903 EUR
Paese: EU
Descrizione
Mental ill-health is one of the biggest challenges for today’s society. Mental disorders are widespread and pervasive, yet our traditional approach to treating patients is archaic, ignoring clinical heterogeneity and their neurobiological causes. Obsessive-Compulsive Disorder (OCD) is a paradigmatic case, where – despite its pervasiveness – many treatments have been discovered serendipitously, where the gold-standard treatments have not changed substantially for decades despite their modest effect sizes, and where highly diverse symptom profiles between patients often go unaccounted for.
CoNbI-OCD will capitalise on the recent advances in computational neuroscience and artificial intelligence to build novel, technologically-advanced, personalised, and mechanism-informed interventions for OCD. By infusing psychotherapy with cutting-edge neuroscience tools, computational modelling, and generative artificial intelligence, I will build new interventions that (i) deliver automated and safe clinical assessments and psychotherapeutic interventions using advanced generative AI, (ii) exploit our ability to decode thought content using neuroimaging tools to objectively measure and target (traditionally inaccessible) obsessions, and (iii) improve individual-specific neurocognitive biases using tailored cognitive and psychotherapeutic interventions. By closely collaborating with the lived experience community and mental health practitioners, I will build clinically relevant and easily transferable interventions to propel existing therapies forward.
This project addresses an urgent need and will bring OCD treatment to the 21st century, developing technologically cutting-edge and personalised interventions that can seamlessly augment the existing gold-standard treatments. CoNbI-OCD has thus the potential to transform how we treat OCD and can evoke a paradigm shift across all of mental health by spearheading disruptive, novel, and personalised treatment avenues.
Settori: computational psychiatry, obsessive-compulsive disorder (OCD), interventions, computational neuroscience
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