[R21] Prolonged Autoantigen Expression via OralDNA Vaccination to Reestablish Immune Tolerance
Ente: National Institute of Allergy and Infectious Diseases
Scadenza: 2028-04-30
Importo max: $246,750
Paese: US
Descrizione
Project Summary
Antigen-specific immunotherapy (ASIT) for Type 1 diabetes (T1D) aims to reinstate robust and durable tolerance
to beta-cell antigens. However, responsiveness to these therapies appears to be dependent on delivering the
right set of epitopes to each patient for proper HLA binding and
Settori: National Institute of Allergy and Infectious Diseases
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