[R03] Role of Maternal MCM4 in Zygotic DNA Replication and Oocyte-to-Embryo Transition
Ente: Eunice Kennedy Shriver National Institute of Child Health and Human Development
Scadenza: 2028-04-30
Importo max: $157,427
Paese: US
Descrizione
PROJECT SUMMARY
Faithful DNA replication is essential for genome integrity and successful embryonic development. During the first
mitotic division of the mammalian zygote, genome duplication is exclusively dependent on maternal replication
factors deposited during oogenesis. The MCM2-7 helicase comp
Settori: Eunice Kennedy Shriver National Institute of Child Health and Human Development
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