[R01] Mechanisms of Biguanide Sensitivity in GBM

Ente: National Institute of Neurological Disorders and Stroke

Scadenza: 2027-04-30

Importo max: $455,380

Paese: US

Descrizione

Project Summary/Abstract The biguanide drug metformin that is widely used for the management of Type 2 diabetes is being evaluated as an anti- neoplastic agent in cancer trials including GBM (NCT02780024, NCT03243851). The various mechanisms of action of metformin as an anti-neoplastic agent is stil

Settori: National Institute of Neurological Disorders and Stroke

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