[F32] Development of a Three-Component Iron-Catalyzed Difluoromethylation Reaction
Ente: National Institute of General Medical Sciences
Scadenza: 2029-05-31
Importo max: $75,880
Paese: US
Descrizione
Project Summary/Abstract
The incorporation of difluoromethyl (–CF2H) group has become a leading strategy in pharmaceutical
development to enhance drug performance due to –CF2H’s unique and profound bioisosteric activity for
hydroxyls, amines, and thiols as a result of its hydrogen bond ability. Pre
Settori: National Institute of General Medical Sciences
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