[R01] Identifying drug tolerance mechanisms in Mycobacterium tuberculosis glpK mutants to develop better treatments against drug tolerant persister bacilli.
Ente: National Institute of Allergy and Infectious Diseases
Scadenza: 2031-05-31
Importo max: $811,772
Paese: US
Descrizione
ABSTRACT
Treatment for tuberculosis (TB) requires adherence to complex, lengthy, and often toxic multi-drug regimens,
which predisposes to treatment failure and relapse. These adverse outcomes appear to be due in part to drug
tolerant populations of Mycobacterium tuberculosis (Mtb), the causative a
Settori: National Institute of Allergy and Infectious Diseases
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