[R01] Adaptive, Regionally- and Individually-Tailored, AI-Based Intervention to Increase HIV Testing and Prevention in Philadelphia
Ente: National Institute of Mental Health
Scadenza: 2031-05-31
Importo max: 812.484 EUR
Paese: US
Descrizione
PROJECT SUMMARY
This ambitious research project will test the effectiveness and dissemination of a digital
intervention to promote home HIV testing and linkage to PrEP (Pre-Exposure Prophylaxis)
among Men who have Sex with Men (MSM) in Philadelphia. In alignment with the
strategic priorities of the Office of HIV Health in the Philadelphia Department of Public
Health (PDPH), the experimental arm will deliver tailored social-media and SMS messages
and nudges generated by a local Community Advisory Board (CAB) and Al-driven
algorithms. We will randomize MSM participants (N = 1,000) to one of two conditions.
The standard of care arm will involve the PhillyKeepOnLoving social marketing campaign
that the PDPH is currently implementing and future city campaigns. The primary
effectiveness outcome is annual routine HIV testing and PrEP (2 HIV tests at least 4 months
apart from one another for HIV-negative participants and PrEP), and secondary
effectiveness outcomes are ART uptake and retention, as well as sexual risk behavior.
Implementation outcomes include reach, adoption, implementation, and maintenance, and
dissemination outcomes include the number of shares and likes of the messages from the
campaign. We will also evaluate mediators, including the personal relevance and
trustworthiness of the messages, as well as motivation, information, and behavioral skills
to seek services. This trial, led by an outstanding team and involving institutions committed
to successful HIV prevention, will help to advance the Respond pillar of the Ending the
HIV Epidemic (EHE) initiative. Through a novel synergy, the proposed research may
transform how future campaigns are conducted to engage participants in HIV prevention
leveraging LLMs (Large Language Models) and community engagement.
Istituzione: UNIVERSITY OF PENNSYLVANIA
PI: DOLORES ALBARRACIN, Jose Arturo Bauermeister
Progetto: 1R01MH140783-01A1
Settori: National Institute of Mental Health
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