[R01] In vivo CRISPR engineering of B cells to produce anti-HIV broadly neutralizing antibodies using novel nanoparticles

Ente: National Institute of Allergy and Infectious Diseases

Scadenza: 2027-05-31

Importo max: $717,470

Paese: US

Descrizione

PROJECT SUMMARY / ABSTRACT The quest for an HIV cure remains incomplete, nearly half a century since the onset of the epidemic. Antiretroviral drug cocktails can suppress HIV infection, but suffer in their success owing to side effects and limitations in access and compliance. Injection of broadly n

Settori: National Institute of Allergy and Infectious Diseases

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