[R01] Characterizing the Mechanism of DPP8/9 Inhibitor-Induced Pyroptosis
Ente: National Institute of Allergy and Infectious Diseases
Scadenza: 2028-05-31
Importo max: $523,794
Paese: US
Descrizione
PROJECT SUMMARY
Several human pattern-recognition receptors detect intracellular danger-associated signals, oligomerize into
multiprotein complexes called inflammasomes, and trigger a lytic form of cell death called pyroptosis.
Inflammasomes are involved in mounting immune responses to pathogens and
Settori: National Institute of Allergy and Infectious Diseases
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