[R21] Combining CRISPR-Cas9 base editing and proteomics to determine how filovirus VP24 proteins modulate ubiquitination and viral replication
Ente: National Institute of Allergy and Infectious Diseases
Scadenza: 2028-05-31
Importo max: $462,000
Paese: US
Descrizione
Summary
The filovirus family includes deadly, emerging/re-emerging, zoonotic viruses such as Marburg virus (MARV) and
Ebola virus (EBOV). A recently described filovirus is Měnglà virus (MLAV) which was identified in a Rousettus
bat in China. VP24 proteins are unique to the filoviruses, engage key ce
Settori: National Institute of Allergy and Infectious Diseases
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