[R01] Role of Protein Tyrosine Phosphatase 1B in Cardiac Hypertrophy
Ente: National Heart Lung and Blood Institute
Scadenza: 2028-05-31
Importo max: $530,541
Paese: US
Descrizione
Project Summary
Oxidative stress is associated with reduced left ventricular (LV) function and correlates with the severity of heart
failure in patients. We have recently demonstrated that Protein Tyrosine Phosphatase 1B (PTP1B) becomes
reversibly oxidized and inactivated in pressure overload-induce
Settori: National Heart Lung and Blood Institute
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