Hijacking Hinges: Cracking the coiled-coil code to control intracellular transport

Ente: WT

Scadenza: 2031-06-01

Importo max: 787.363 €

Paese: EU

Descrizione

Kinesin and dynein motors transport cargo bidirectionally along microtubules. Proper regulation is essential for cellular health, and its disruption is linked to neurodegeneration, cardiac disease, and cancer. Motor proteins and adaptors are autoinhibited and activated by specific motor-cargo–adapto

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