Myeloid Inhibitory C-type lectin-like receptor (MICL, CLEC12A) – a central regulator of immunity

Ente: WT

Scadenza: 2034-05-31

Importo max: 4.652.170 €

Paese: EU

Descrizione

My group recently discovered that functional loss of the inhibitory C-type lectin receptor MICL on neutrophils, through either genetic deletion or in the presence of autoantibodies, leads to inflammatory pathology that exacerbates autoimmune diseases. In contrast, loss of MICL function was protectiv

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