[T32] Training Program for Applied Research and Development in Genomic Medicine
Ente: National Human Genome Research Institute
Scadenza: 2028-04-30
Importo max: 592.755 EUR
Paese: US
Descrizione
ABSTRACT
Healthcare professionals, genomic scientists, and numerous other stakeholders are embracing advances in healthcare, with an increasing frequency being delivered through approaches that
employ genomics to improve care and patient outcomes. To ensure that we can continue to expand upon and deliver the full potential of such an approach requires a highly qualified cadre of
clinician-scientists, scientists, and clinicians working collaboratively to advance discoveries and implementation in genomic medicine. This proposal for continuation of our post-doctoral genomic
medicine training program, “Program for Applied Research and Development in Genomic Medicine,” (PARADIGM) leverages our successes and lessons learned from the first cycle of
funding to: 1) refine an integrated training program in genomic medicine, which includes didactic, research, clinical, and professional development activities; 2) recruit promising junior investigators
and train them using an interprofessional and interdisciplinary mentoring approach; and 3) evaluate the PARADIGM training program for achievement of learning objectives, success, and
long-term productivity and career progress of trainees. This training program for MDs, PharmDs, PhDs, and other clinical specialists at the doctoral level is based on four premises: 1) Genomic
medicine must be advanced by a cadre of clinicians and PhD scientists from a variety of specialty areas; 2) a team approach is essential; 3) genomic medicine will require an extensively skilled
workforce of leaders; 4) the University of Florida is an ideal environment for this training. To train individuals to meet these needs, PARADIGM will provide a multi-year, integrated,
multidisciplinary program comprised of four major components: 1) a Didactic component of required and optional coursework; 2) a Mentored Research component involving a defined
research project under the mentorship of an accomplished genomic medicine scientist and clinician; 3) a Clinical Genomic Medicine component that integrates trainees into the genomic
medicine clinical practice setting; and 4) a Professional Development component including training in research integrity; administrative, fiscal, and regulatory training; and grant-writing skills.
Training across these four components will be tailored to the experience and needs of each trainee, but will be concentrated in three cores of expertise at UF: pharmacogenomics, cancer
genomics, and disease susceptibility genetics/genomics. The program will be led by two highly accomplished leaders in the field together with a cadre of highly talented, collaborative,
multidisciplinary mentors. PARADIGM will undergo continuous evaluation and quality improvement to ensure long-term success of the trainees. Upon program completion, each
trainee will be expected to possess knowledge and skills that will enable them to manage the challenges of evidence generation and clinical use of genomic medicine.
Istituzione: UNIVERSITY OF FLORIDA
PI: Larisa Humma Cavallari, Stephen E. Kimmel
Progetto: 5T32HG008958-09
Settori: National Human Genome Research Institute
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