[T32] Studies in Translational Regenerative Medicine
Ente: National Institute of Biomedical Imaging and Bioengineering
Scadenza: 2031-06-30
Importo max: 111.926 EUR
Paese: US
Descrizione
PROJECT SUMMARY
The Regenerative Medicine (RM) field requires a unique type of researcher, well-trained in fundamental RM
concepts and methods, able to integrate human biology and engineered systems with awareness of challenges
involved in advancing basic research, regulatory science, and clinical translation. The overall goal of our T32
pre-doctoral training program, “Studies in Translational Regenerative Medicine”, remains committed to
developing next generation multidisciplinary trained research scientists and engineers, who will lead
new innovative research teams designing solutions to real-world health problems. Ability to link state-of-
the-art multidisciplinary basic science training to the infrastructure and knowledge base required to accelerate
translation of RM technologies are key strengths. To date, this T32 program has provided 11 PhD trainees the
tools to become independent RM researchers in a variety of successful career trajectories. Consistent with
faculty’s successful record, our T32 program has met and exceeded goals. Trainees accrued an impressive list
of high-quality publications (46 publications, 11 under review/in process) and oral and poster presentations (76
presentations; 35 oral and 41 poster) at local to international meetings. Significantly, 100% of all T32 appointed
trainees have obtained the PhD or remain in their PhD program with defense planned in the next year or two
(100% retention). Five of the trainees have continued on as investigators in translational RM research into
prominent industry-sector careers, with ongoing collaborations across academic and government sectors. Three
(60%) were recruited by industry with RM portfolios “specifically” because of their T32 training. WFIRM’s
distinctive infrastructure and ever-expanding multidisciplinary training environment provides the facilities and
expertise for translational studies ranging from basic preclinical studies through Phase 2 clinical trials. WFIRM’s
multidisciplinary training includes a range of activities, including didactic courses, cutting-edge team science,
and new opportunities to engage in industrial externships. Our program also emphasizes professional
development including grant writing, regulatory science, GMP manufacturing, and scientific ethics. The program
has 3 NIBIB-aligned focus areas: 1) tissue engineering (bioprinting/biomaterials); 2) enabling technologies (body-
on-a-chip, imaging, machine learning/AI); and 3) stem cells/cell therapies which is applied to several application
areas: 1) cardiovascular; 2) musculoskeletal; 3) gastrointestinal/endocrinal; 4) reproductive; and 5) neurological.
Trainees are selected from 4 WFGS tracks: Molecular & Cellular Biosciences, Neuroscience, Biomedical
Engineering, or Integrative Physiology and Pharmacology. After their 1st year, trainees identify one of 19 primary
mentors (of 28 mentoring faculty), take specialized RM courses, and form a thesis committee. Inclusion of
seasoned Primary Mentors (17),
Istituzione: WAKE FOREST UNIVERSITY HEALTH SCIENCES
PI: ANTHONY ATALA, Victoria Weis
Progetto: 2T32EB014836-11
Settori: National Institute of Biomedical Imaging and Bioengineering
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